Dr. Subhash Basu, professor emeritus of chemistry and biochemistry, will embark on a speaking tour of India on Tuesday to discuss his current research on potential new anti-cancer drugs. Basu will make his second appearance at the International Cancer Research Symposium on Dec. 19 in Calcutta when he gives a lecture titled “Probable New Therapeutic Drugs for Breast and Colon Cancers.” “The invitation to this symposium is very prestigious. Sixty people from all over the world are going to Calcutta,” he said. “I will tell them what our plan is for the delivery of these new anti-cancer drugs.” Basu’s lecture tour will also include an appearance at the Indian Science Congress on Jan. 4, where he will discuss the apoptotic, or cell-killing, effects of the drugs he is working with his collaborators to develop. “Our work is important, and we get an invitation every year to speak at these sorts of things,” he said. Basu said he and his research team have discovered five to six different new anti-cancer compounds that would be useful for treating colon and breast cancer patients. “These chemicals are quite toxic to biological cells and they kill cancer cells by enhancing apoptosis, or programmed cell death, in a very micro amount,” he said. Now that these cancer-killing compounds have been discovered, Basu said the main goal of his work is to determine ways to deliver the drugs into patients at the location of the cancer without harming the healthy cells around the cancerous ones. “Cancer cells normally die of necrosis – they make holes in themselves,” he said. “When apoptosis happens, the cell gets bigger and its DNA starts degrading until the cell cannot function.” Basu said about 50,000 women die of breast cancer in the United States each year, so his research could impact thousands of lives in the future. “Chemotherapy could be improved by our procedure by giving patients micro doses of drugs so they don’t kill the normal cells,” he said. “Thus, the success of these apoptotic chemicals as anti-cancer drugs depends on their proper delivery to the cancer sites.” To facilitate and fund his research in this area, Basu founded the Cancer Drug Delivery Research Foundation (CDDRF) in 2010, of which he serves as president. The foundation received its first major source of support when the University transferred all of Basu’s recoupment to CDDRF in May, he said. “All this recoupment was brought in by me from federal grants and other sources during my time at the University,” Basu said. “This foundation is tax-exempt and will help only for my research, so any patent money we get can go into the research as well.” Basu said his status as a permanently appointed emeritus professor gave him the freedom to move his lab from campus to a currently undetermined site near campus. “The University said I would have to give half of whatever I bring in to Notre Dame if I continue to work in a lab here,” he said. “It becomes cheaper for me to run my lab outside because I can use 100 percent of my money for research.” Since joining the faculty at Notre Dame in 1970, Basu has received major grants from the National Institutes of Health and the National Cancer Institute.
Broadway vet and Ghostbusters mayor David Margulies died on January 11, reports the New York Daily News. He was 78 years old.Margulies was born in Brooklyn, New York, the son of Runya and Harry David Margulies, a nurse and lawyer, respectively. Soon after graduating from the City College of New York, Margulies made his stage debut in 1958’s Golden 6 off-Broadway.It was in 1973 that Margulies made his Broadway debut in The Iceman Cometh; he later went on to tread the Main Stem’s boards in Zalmen or The Madness of God, Comedians, Break a Leg, The West Side Waltz, Brighton Beach Memoirs, Cafe Crown, Conversations With My Father, Angels in America, A Thousand Clowns and 45 Seconds From Broadway. Margulies was last seen on the Great White Way in the 2003 revival of Wonderful Town.An off-Broadway mainstay, Margulies’ most recent credits included After the Revolution at Playwrights Horizons, All That I Would Ever Be at New York Theatre Workshop, The Accomplices at the Acorn Theatre and The Illusion at Signature Theatre Company. His last stage appearance was in 2013—The Hatmaker’s Wife for Playwrights Realm.Marguiles’ best known film role was as the Mayor of New York in the blockbuster movies Ghostbusters and Ghostbusters II. Additional screen credits included Ace Ventura: Pet Detective, A Most Violent Year, The Front, All That Jazz, Dressed to Kill, 9½ Weeks and The Sopranos. He will soon be seen as Elie Wiesel in ABC’s upcoming series Madoff. View Comments
By Brad HaireUniversity of GeorgiaAfter back-to-back punches from the tropics, Georgia farmers are happy to see the return of sunnier, drier weather.The damage from Hurricanes Frances and Ivan was worse for some crops than others and worse in some places than others, say University of Georgia experts.Pecan production in Georgia was hurt by both storms. About 25 to 30 percent of the pecan crop has been lost around Dougherty County, where much of the state’s pecan crop is grown, said Lenny Wells, a UGA Extension Service agent in Dougherty County.The pecan crop was reported to be hurt in Lowndes, Lanier and Berrien counties, too. Most of the damage was from downed trees and limbs and nuts blown from trees.And the damage may be felt for years to come, Wells said. Young trees that were blown down can be propped back up. But they can have problems getting back into a production rhythm. Mature trees that were uprooted probably can’t be saved.”It will take four to six years for replacement trees to bear again,” Wells said, “and 15 years or so to make it back to full production.”Georgia’s pecan harvest will begin in late October and run through December.About 20 percent of Georgia’s cotton crop has been lost to the storms’ excessive rains and winds, said Steve Brown, a UGA Extension cotton agronomist.Western counties were hit harder by Ivan’s winds and rains. “Their losses may have been higher,” Brown said.Georgia’s most widely planted cotton variety hasn’t been very stormproof. “It readily falls out once it has opened and subjected to rain and wind,” he said.Cotton picked before the storms was of good to excellent quality, he said. But the harvest is just beginning. There’s still a lot of cotton left to pick.”The bright sunshine of the past several days has been a real positive to Georgia cotton,” Brown said.Peanut farmers are taking advantage of the drier weather, too. Frances and Ivan didn’t cause too much trouble for the state’s peanut farmers. The rain from Frances actually did more good than harm.But the wet, humid weather between the two storms delayed harvest and increased disease pressure in fields, said John Beasley, a peanut agronomist with the UGA Extension Service.”We had several days of rainy, overcast weather that didn’t allow us to dry out any and maybe even harvest some between the two systems,” Beasley said.Georgia’s vegetable crop wasn’t widely damaged. “But there was some locally heavy damage in individual cases,” said UGA Extension horticulturist Terry Kelly.The moisture and cloudy days of September so far have caused pollination problems for some vegetables. It’s also made it tough for farmers to apply needed pesticides.”It has made disease more likely,” Kelley said. “It generally causes a decrease in growth and development of the plants.”On Thursday, forecasters weren’t sure where or if Hurricane Jeanne would hit the southeastern U.S. coast. Nov. 30 is generally considered the end of hurricane season.
David Walker, former U.S Comptroller General and now President of the Peter G. Peterson Foundation, will speak at the Sheraton Burlington Conference Center on Thursday morning, August 19, on the subject of his most recent book Comeback America: Turning the Country Around and Restoring Fiscal Responsibility.Since moving to the Foundation in 2008, Walker has appeared on a nationwide Fiscal Wake Up Tour in some 45 states, speaking on America’s growing fiscal and debt problems. As a CPA and head of the Government Accountability Office for almost ten years, Walker is one of the most knowledgeable persons in the country on the long run outlook for federal finances – and the impacts on social security, Medicare, and other key programs.Responding to Walker’s presentation will be a panel of three well-known and knowledgeable Vermonters:Ø Dr. Art Woolf, UVM associate professor of economics and former state economistØ David Coates CPA, retired partner, KPMG and expert on post retirement benefitsØ Tom Salmon CPA, Auditor of Accounts, andØ Mary Alice McKenzie, moderator.The program will run from 9:00 to noon. The public is invited, there is no admission charge, and reservations are not required. Walker’s most recent book will be available for purchase.“Vermonters are fortunate in being able to meet and hear from this leading national figure, who really understands our nation’s deteriorating finances and has a strong program for turning our country around,” said EAI President John McClaughry.Walker drew over five hundred listeners when he spoke last year at the Todd Distinguished Lecture Series at Norwich University. He recently gave invited testimony to the President’s bipartisan debt commission, and has been on numerous radio and television programs.Walker’s Burlington appearance is part of the Sheraton Economic Series, sponsored by the Ethan Allen Institute, hosted by the Sheraton Burlington, and co-sponsored by the Lake Champlain Regional Chamber of Commerce, Vermont Business Magazine, Vermont Tiger, and the Vermont Economic Newsletter.For more information, visit www.ethanallen.org(link is external) or email firstname.lastname@example.org(link sends e-mail).#####
FacebookTwitterLinkedInEmailPrint分享S&P Global Market Intelligence ($):More than twice the size of the largest battery system currently operating in the United States, the AES Alamitos Energy Battery Storage Array in Long Beach, Calif., signals much bigger things soon to come for electrochemical energy storage on U.S. power grids.This first 100-MW/400-MWh phase of the system, on which owner AES Corp. recently broke ground, is underpinned by a 20-year contract with Southern California Edison Co. starting in December 2020. Relying on lithium-ion batteries, the system could eventually triple in size with its permit to expand to 300 MW.Among contracted U.S. battery storage projects, the Alamitos array is surpassed by Vistra Energy Corp.’s 300-MW/1,200 MWh Vistra Moss Landing Energy Storage system, near Santa Cruz, Calif., which has a 20-year agreement for the entire installation with Pacific Gas and Electric Co., or PG&E. Co-located at another major combined-cycle gas plant, Vistra’s Moss Landing CC, the project is also scheduled to start operations in December 2020.Planned to come online at the same time and in the same place is the PG&E Corp. subsidiary’s 182.5-MW Tesla Moss Landing Battery Energy Storage Project (Elkhorn), an approved utility-owned project to be supplied by Tesla Inc. Other major utility-scale battery projects, some coupled with solar farms, are planned around the country, including in Arizona, Colorado, Florida, Hawaii, Nevada, New York and Utah.While the PG&E projects could see delays, or even cancellations, related to the utility’s ongoing Chapter 11 bankruptcy and restructuring process, batteries could ultimately satisfy “a substantial portion of U.S. peak capacity needs,” the U.S. Department of Energy’s National Renewable Energy Laboratory, or NREL, concluded in a new report, “The Potential for Battery Energy Storage to Provide Peaking Capacity in the United States.” Assuming current conditions and demand patterns on the U.S. grid, the analysis identified a practical energy storage peak power potential of about 70,000 MW. That includes approximately 28,000 MW from four-hour battery storage arrays, 8,000 MW from six-hour storage systems and 34,000 MW from eight-hour storage projects.More ($): AES starts building largest battery peaker, highlighting technology’s potential AES breaks ground on largest battery storage unit in the U.S.
The actress, who has lost her mother, grandmother and aunt to cancer, made the announcement in the New York Times. Hollywood actress Angelina Jolie has had her ovaries and fallopian tubes removed.The actress made the announcement on Tuesday saying she made the decision to remove her reproductive organs for fear of getting cancer.Jolie had a double mastectomy two years ago where she had both of her breasts removed after doctors told her that she had very high chances of getting cancer.The actress, who has lost her mother, grandmother and aunt to cancer, made the announcement in the New York Times.The Hollywood superstar carries a gene mutation that had given her an 87 percent risk of developing breast cancer and a 50 percent risk of developing ovarian cancer.Angelina Jolie has revealed that she underwent preventative surgery to have her ovaries and fallopian tubes removed last week after tests found inflammatory markers that could be an indication of cancer.Jolie, who had a preventive double mastectomy in 2013 when genetic tests showed an 87 percent risk of breast cancer, wrote in a New York Times that the also had a 50 percent risk of ovarian cancer.As a result, the 39-year-old filmmaker, actress, UN envoy and mother of six had been planning to undergo the procedure for some time.“It is a less complex surgery than the mastectomy, but its effects are more severe. It puts a woman into forced menopause,” Jolie wrote.“So I was readying myself physically and emotionally, discussing options with doctors, researching alternative medicine, and mapping my hormones for estrogen or progesterone replacement. But I felt I still had months to make the date.”When she learned two weeks ago that tests revealed higher inflammation levels, Jolie and her doctors decided it was time. Her husband, actor Brad Pitt, who was in France at the time, flew to be with her during the procedure, a laparoscopic bilateral salpingo-oophorectomy.
Chelsea reportedly offered Michy Batshuayi and Ross Barkley to West Ham in an £80million deal for Declan Rice. But The Times reports the Hammers rejected the swap deal and are holding out for £80m in cash. David Moyes’ side are not interested in taking on the rarely used pair. Both Barkley and Batshuayi have had peripheral roles in Frank Lampard’s Chelsea set-up. But the club were hoping to bring down the massive price tag on Rice’s name by offering some of their unwanted stars as a makeweight. Chelsea were hopeful as West Ham previously tried to sign Batshuayi and Moyes coached Barkley at Everton, but it appears to have done them no favours. Blues boss Lampard is desperate to bring in reinforcements to fix his leaky defence. Chelsea conceded more goals than any other side in the Premier League’s top ten last season and has identified Rice as a potential solution.Advertisement The 21-year-old was released by the Blues as a teenager before joining West Ham aged 14. Rice played every minute of every league game last term, but mainly in his usual position of central midfield. However, Lampard is keen to use his versatility and convert him into a talismanic centre-back. And fans were convinced Rice would return to Chelsea after being spotted with “agent” John Terry. read also:Former Chelsea star brings ‘Rice’ to Stamford Bridge Rice posed with the former Stamford Bridge hero in a post shared to Instagram by Aston Villa’s assistant manager. And Lampard is hopeful he could have a similar impact to Terry if he can lure the England international back to West London. Rice is currently on holiday with best mate and Chelsea star Mason Mount. FacebookTwitterWhatsAppEmail分享 Loading… Promoted ContentBest & Worst Celebrity Endorsed Games Ever Made6 Ridiculous Health Myths That Are Actually True7 Universities In The World With The Highest Market Value8 Things You Didn’t Know About CoffeeWho Is The Most Powerful Woman On Earth?The Very Last Bitcoin Will Be Mined Around 2140. Read More9 Facts You Should Know Before Getting A TattooWho Earns More Than Ronaldo?8 Addictive And Fun Coffee FactsWhat’s Up With All The Female Remakes?7 Reasons Why You Might Want To Become A VegetarianBirds Enjoy Living In A Gallery Space Created For Them
One point separates them from safety in what has developed into a fraught relegation battle, with every team from Hull, in 13th, downwards still in danger of the drop. Magath, who insists he will be reading German crime fiction to help calm his nerves over the coming days, has never been relegated in his 19-year managerial career. “I’m afraid for the club, not for my personal record. I have nothing to prove in my career,” he said. “I knew it was a difficult situation when I came here. I’m confident I can manage it. “I worry a little bit about the last matches but I’m confident. We can make it better on Saturday.” With Fulham’s Premier League survival hanging by a thread, Magath is wary of using the Greece striker at this stage of the season and will not be influenced by his price tag. “Kostas is part of our team now and he can play again this season,” Magath said. “I feel pressure to pick the best 11. It is not just black and white when you consider a player, you must think about how to get the best from him. “He’s a player who is very dangerous in the box. At the beginning, as we played, we weren’t coming into the box. “It was not the right situation for him. Now we are creating some chances and coming into the box. In the box he is very good. “Kostas wants to play and will help us. You never know if he has not played how he will realise his abilities in a game. “You can try in training sessions but it is not the same situations in training sessions as in games.” Magath accepts that only victories against Stoke at the Britannia Stadium on Saturday and against Crystal Palace at Craven Cottage eight days later will give Fulham a chance of staying in the top flight. Mitroglou is finally available to join the squad for Saturday’s Barclays Premier League clash at Stoke after almost two months out with a persistent knee problem. The £12milllion accusation on transfer deadline day has made just two appearances since his arrival in January. Felix Magath feels no pressure to pick Fulham’s record signing Kostas Mitroglou for the last two matches of the season. Press Association
Bournemouth made it two strikers in as many days as they snapped up Lewis Grabban from Norwich. Former Rotherham player Grabban, 27, helped Norwich earn promotion to the Barclays Premier League last season. “I think we’ll be getting a better Lewis Grabban, but he’ll realise that we’ve got better as well and he will have to adapt too. But we’re in no doubt we’re getting a good player back,” manager Eddie Howe told his club’s official website. “He’s also someone who was popular in the dressing room behind the scenes he’s a strong motivator and we’re delighted to be bringing him back.” Earlier, Howe had spoken of his excitement at the potential of Afobe but is determined not to place any pressure on the young striker to make an immediate impact. Afobe, 22, joined the Cherries from Sky Bet Championship side Wolves for an undisclosed fee on Sunday and has signed a four-and-half-year deal. The former Arsenal player has been a regular goalscorer in the lower leagues, including a prolific stint with MK Dons last season, and Howe believes he has ability to do well in the top flight as well. “He is entering a new league and that is going to be a big experience for him but we believe he can make the step up,” Howe told a press conference. “He is strong, you just look at him and know he is going to be a handful, but he has good technique. “I am excited by that because I think there is a lot of potential in him and he is a really good age, and I think there are a lot of good years ahead of him.” It remains to be seen when Afobe will make his Bournemouth debut, with the striker waiting for clearance to see if he will be available to face West Ham on Tuesday, but whatever happens Howe does not want to put too many demands on his new player straight away. Howe added: “He may need a little bit of time to settle as most new players do for us because of the way we play, so we are not placing huge expectation on his shoulders. “He is someone who can play the role the way we like it to be played and I think he will be a success, but we are going to need to work on him like we do all other players.” Although he has already made two early swoops in the transfer market, Howe is still confident of attracting more players to Bournemouth before the window closes. “We are still looking, no guarantees but we are hoping to add to the squad,” the 38-year-old said. “Like any transfer window it is an important window, we want to try and bring the right players to the club with the right attitudes. “I have been excited by the signings we have had so far, if we can add a bit more quality then I think we will be in a really healthy position.” The Cherries have paid an undisclosed fee for Grabban, who returns to the south coast for a second spell. Grabban – who scored 35 goals during his first two-year stay – joins on a three-and-a-half-year deal and his arrival comes a day after the capture of Benik Afobe from Wolves. Press Association
Syracuse University appoints diversity director for sportsSYRACUSE, N.Y. (AP) — Syracuse University has added an athletic director of diversity, culture and climate in a new position within the department of athletics. Salatha Willis is charged with developing and implementing new ways to create an equitable culture for the university’s student-athletes, administrators, coaches and staff in the athletic department. The move is a response to the racial tension that has wracked the country, including a period of social unrest on campus last fall. There were more than a dozen reports last November of racist graffiti and vandalism targeting Blacks, Jews, Asians and Native Americans. Share This StoryFacebookTwitteremailPrintLinkedinRedditWIMBLEDON-PRIZE MONEYWimbledon to allocate prize money despite cancellationWIMBLEDON, England (AP) — Wimbledon will pay out $12.5 million in prize money to 620 players despite the tournament’s cancellation because of the coronavirus pandemic, the All England Club said Friday. Associated Press In a letter posted Thursday on their respective Twitter accounts, they said: “Speaking out is something we’ve both felt we really needed to do for a long time now, but in truth, we’ve been afraid to do so.”Both women represented Britain in the 2016 Olympic Games but they say their success has come at a high price.Twenty-eight-year-old Becky said she was called “mentally weak” for questioning her training regimen in 2018. She then injured her ankle in “a direct consequence of the unsafe training.” Her 20-year-old sister said a nutritionist required her to send daily pictures of herself wearing just underwear to prove she wasn’t gaining weight. She was 14 years old at that time.British Gymnastics CEO Jane Allen this week announced an independent review of claims of mistreatment. She said the British Gymnastics Integrity Unit already exists to investigate allegations and that there are welfare officers around the country.SYRACUSE-DIVERSITY DIRECTOR TOKYO (AP) — Japan’s professional baseball league opened the delayed season three weeks ago. Now fans are back, too.After playing in empty stadiums to get started, Japan began allowing up to 5,000 fans into the games on Friday, or 50% of the stadium capacity — whichever is smaller. Officials hope to allow stadiums to be filled to 50% capacity beginning on Aug. 1.Japan’s soccer J-League is also allowing fans to return, beginning on Friday, under the same guidelines.Fans are required to use hand disinfectant and have their temperatures taken when they entered the stadium. Shops were open and food and drinks were for sale, but alcohol was not allowed.Restrictions were also put on the amount of cheering permitted, a staple at games in Japan. Update on the latest sports After consulting with its insurance provider, club officials said 256 players who would have competed in the main draw will each receive 25,000 pounds ($31,000), while 224 players who would have competed in qualifying will each receive 12,500 pounds ($15,600).In addition, 120 players who would have competed in doubles will each receive 6,250 pounds ($7,800); 16 players who would have competed in the wheelchair events will each receive 6,000 pounds ($7,500); and four players who would have competed in the quad wheelchair events will each receive 5,000 pounds ($6,200).All England Club chief executive Richard Lewis said “we are pleased that our insurance policy has allowed us to recognize the impact of the cancellation on the players.”JAPAN-FANS RETURNBaseball is back in Japan, and so are fans in the stadiums Japan has been largely successful controlling COVID-19 with about 1,000 deaths attributed to the coronavirus pandemic. The United States, with a population about 2 1/2 times larger, has recorded more than 130,000 deaths. However, Tokyo has reported more than 200 new cases in each of the last several days. That is the highest number in the Japanese capital since April.GYMNASTICS-BRITAIN-ABUSE COMPLAINTSBritish Olympic gymnasts decry ‘abusive behavior’LONDON (AP) — British Olympians Becky and Ellie Downie say they’ve suffered from abusive behavior in gymnastics training for many years, adding their voices to a growing number of gymnasts coming forward with similar complaints.The sisters said coaches pressured them to lose weight and overtrain, which took mental and physical tolls. They were inspired to tell their story after former teammates did the same. July 10, 2020